Hematopoietic cell transplantation with autologous cord blood in patients with severe aplastic anemia: an opportunity to revisit the controversy regarding cord blood banking for private use.
نویسندگان
چکیده
The controversy surrounding private banking of umbilical cord blood units (CBU), as a safeguard against future malignancy or other life-threatening conditions, raises many questions in pediatric clinical practice. Recent favorable experiences with autologous transplantation for severe aplastic anemia using privately stored CBU, suggested a possible utility. While private banking is difficult to justify statistically or empirically, there may exist rare cases where autologous transplant of stored umbilical CBU could be beneficial. The reality of privately banked CBU and the possibility for future discovery of additional indications for autologous cord blood transplant, motivated us to re-examine our attitudes towards private cord blood banking.
منابع مشابه
A Review of Procedures Involved in Human Umbilical Cord Blood Banking and Transplantation
Cord blood hematopoietic stem cells are widely used as an alternative source for hematopoietic stem cells transplant. Increasing rate of patients who need hematopoietic stem cells transplant and many advantages of cord blood in comparison to bone marrow hematopoietic stem cells, have promoted banking of cord blood units. Cord blood banking requires accurate steps in donor selection, cord blood ...
متن کاملThe successful treatment of severe aplastic anemia with autologous cord blood transplantation.
Cord blood transplantation has been used extensively in the allogeneic setting for acquired and genetic disorders of hematopoiesis. There is less experience in the utility of autologous cord blood transplantation, and there is great controversy about the role of autologous cord blood collection and storage. We report on the successful use of autologous cord blood transplantation for the treatme...
متن کاملInm-9: Cord Blood Banks and Cord Blood Donors Selection
Cord blood is a sample of blood taken from a newborn baby's umbilical cord.Cord blood is collected because it is rich in stem cells content, such as hematopoietic cells, which can be used to treat hematopoietic and genetic disorders. Cord Blood Transplantation has been used in the treatment of over 80 diseases, including leukemia, lymphoma and anemia. Advantages of Cord Blood Treatment: • ...
متن کاملInm-9: Global Approach toward Banking Cord Blood Stem Cells
Umbilical cord blood is the baby's blood left over in the umbilical cord and placenta after a baby is delivered and the cord is cut. Cord blood has all of the features of regular blood, but it is also a rich source of hematopoietic stem cells. Hematopoietic stem cells are unspecialized cells that produce all blood cells. These include: • Platelets, which are needed for blood clotting • Red...
متن کاملCord Blood
Stem cells are naïve or master cells. This means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. Stem cells are found in many parts of the human body, although some sources have richer concentrations than others. Some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Pediatric blood & cancer
دوره 56 7 شماره
صفحات -
تاریخ انتشار 2011